a facile synthesis of (s) – (-) – propranolol
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abstract
a one-pot synthesis of (s)-(-)-propranolol is reported. zn(no3)2/(+)-tartaric acid catalyzed enantioselective synthesis of (s)-(-)-propranolol via kinetic resolution of key intermediate ?-naphthyl glycidyl ether with high optical and chemical yield.
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A FACILE SYNTHESIS OF (S) – (-) – PROPRANOLOL
A one-pot synthesis of (S)-(-)-propranolol is reported. Zn(NO3)2/(+)-tartaric acid catalyzed enantioselective synthesis of (S)-(-)-propranolol via kinetic resolution of key intermediate ?-naphthyl glycidyl ether with high optical and chemical yield.
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Journal title:
journal of sciences islamic republic of iranجلد ۱۴، شماره ۱، صفحات ۰-۰
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